Agentic AI in the enterprise is changing the CIO's role faster than most governance models can keep up with. Systems that plan, act, and call tools on their own now sit within workflows the Chief Information Officer no longer fully owns. Meanwhile, boards continue to expect the same level of accountability for security, risk, and value.
CXOTalk episode 919 offers a practical guide and playbook for CIOs on AI strategy, governance, and enterprise transformation. The conversation pairs technical depth with CIO operating experience to address a specific question: what should a Chief Information Officer do this quarter and this year to lead agentic AI?
What we will cover:
- How the CIO mandate shifts from running systems to governing autonomy in an agentic AI enterprise
- Managing trust, data, and control when the middle layer of models, agents, and vendors is opaque
- A realistic response to shadow AI and "vibe coding" that protects the business without blocking it
- Designing human oversight that works at machine speed, before, during, and after AI operates
- Building the operating model, governance, and culture for continuous AI disruption
- Monday morning moves: concrete actions CIOs can take this quarter
Watch episode 919 with Anthony Scriffignano and Tim Crawford live and ask your questions!. Subscribe to the CXOTalk newsletter for the full schedule of upcoming conversations.
Episode Participants
Tim Crawford is a strategic CIO & advisor who works with large global enterprise organizations across a number of industries, including financial services, healthcare, major airlines, and high-tech. Tim’s work differentiates and catapults organizations in transformative ways by leveraging technology as a strategic lever. Tim takes a provocative, but pragmatic approach to the intersection of business and technology.
Anthony Scriffignano, Ph.D. is an internationally recognized data scientist with experience spanning over 40 years in multiple industries and enterprise domains. Scriffignano has an extensive background in advanced anomaly detection, computational linguistics, and inferential methods, and leverages it as the primary inventor on multiple patents worldwide. He also has extensive experience with various boards and advisory groups.
Michael Krigsman is a globally recognized analyst, strategic advisor, and industry commentator known for his deep business transformation, innovation, and leadership expertise. He has presented at industry events worldwide and written extensively on the reasons for IT failures. His work has been referenced in the media over 1,000 times and in more than 50 books and journal articles; his commentary on technology trends and business strategy reaches a global audience.
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